Categories, prototypes and memory systems in Alzheimer's disease

Recent studies indicate that category learning is mediated by multiple neuronal systems. It has been shown that patients with marked impairments in executive functions, explicit memory and procedural learning can categorize the exemplars and prototype of a previously trained category. Simple, self-organizing neuronal networks can explain prototype learning and related dysfunctions in Alzheimer's disease, and provide a model of how prototype learning is mediated by circumscribed mechanisms in the visual cortex.