Panic disorder: a test of the separation anxiety hypothesis |
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| Authors: | B A Thyer R M Nesse G C Curtis O G Cameron |
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| Affiliation: | 1. Skirball Institute of Biomolecular Medicine, Departments of Cell Biology, Physiology & Neuroscience and Psychiatry, New York University, New York, NY 10016, USA;2. New York State Psychiatric Institute, Division of Clinical Phenomenology, 1051 Riverside Drive, New York, NY 10032, USA;3. Columbia University, Department of Psychiatry, New York, NY 10032, USA;4. Mental Illness, Research, Education, and Clinical Center (MIRECC), James J Peters VA Medical Center, Bronx, NY 10468, USA;5. Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA;6. Department of Psychiatry, Social and Psychiatric Initiatives, New York University, 1 Park Avenue, 8th Floor Room 222, New York, NY 10016, USA;7. University at Buffalo, Department of Psychiatry, Buffalo, NY, 14215, USA;8. Genome Technology Center, New York University Langone Medical Center, New York, NY 10016, USA;9. Department of Surgery, Weill Cornell Medical College, New York, NY 10065, USA;1. Psychiatry Research Center, Beijing HuiLongGuan Hospital, Peking University, Beijing, China;2. Department of Psychiatry and Behavioral Sciences, Harris County Psychiatric Center, The University of Texas Health Science Center at Houston, Houston, TX, USA;3. Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA |
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| Abstract: | The DSM-III narrative remarks suggest that childhood separation anxiety disorder and sudden object loss apparently predispose to the development of adult panic disorder, despite the paucity of empirical studies documenting such a relationship. In an attempt to test the validity of this separation anxiety hypothesis of panic disorder, 14 objective questions pertaining to childhood separation experiences were answered by 23 panic disorder patients and 28 small-animal phobics. Although the panic disorder patients scored higher on 2 of the 14 items, these differences appear to have little clinical meaning. Caution is indicated prior to continued uncritical acceptance of the separation anxiety hypothesis of panic disorder. |
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