Das Restless-Legs-Syndrom

In 1995, the International Restless Legs Syndrome Study Group (IRLSSG) developed the first consensus-based diagnostic criteria, which were revised in 2003. These criteria allowed the implementation of numerous epidemiological, pathophysiological, and therapeutic approval studies. To increase the specificity, the guidelines were augmented regarding differential diagnoses, clinical severity, and objective examination in 2012. RLS, one of the most common neurological diseases worldwide, is often misdiagnosed and greatly underdiagnosed. Symptomatic treatment with dopaminergic agents is standard treatment for primary RLS; however, opioids are also used.