肠道菌群与代谢综合征

人类肠道内定植着大量的微生物，肠道菌群通过多种机制参与机体的能量代谢，影响着宿主食物向能量的转化，对宿主的健康有着重要作用，因此，可以将肠道菌群看作是具有多种调节功能的“体外器官”。近年来研究的结果提示人类胃肠道菌群的改变参与了肥胖及胰岛素抵抗的发生。本综述旨在探讨肠道正常菌群与代谢综合征的关系。

Gut Microbiota and its Possible Role in the Pathogenesis of Metabolic Syndrome

The human intestine contains a large variety of microorganisms, which contributes to our homeostasis with largely diversified multiple functions. The biological functions controlled by the intestinal flora are related to the effectiveness of energy harvest, and may play an important role in maintaining human health. Thus, the intestinal flora can be considered as an ＂exteriorized organ＂. Current evidences indicate gut microbiota might be involved in the development of obesity and insulin resistance. This review discussed the possible role of gut microbiota in the development of metabolic syndrome.