The borderline hypertensive rat: a model for studying the mechanisms of environmentally induced hypertension |
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| Authors: | J E Lawler R H Cox B J Sanders V P Mitchell |
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| Affiliation: | Department of Psychology, University of Tennessee, Knoxville 37996-0900. |
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| Abstract: | The borderline hypertensive rat (BHR) is a first-generation cross between the spontaneously hypertensive rat and the normotensive Wistar-Kyoto rat. The BHR develops frank hypertension when chronically stressed or when fed a high-sodium diet. Stress-induced hypertension can be blocked by exercise. The role of the central nervous system and kidney in hypertension development in this model is discussed. |
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