Pavlovian influences on goal-directed behavior in mice: the role of cue-reinforcer relations |
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Authors: | Crombag Hans S Galarce Ezequiel M Holland Peter C |
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Affiliation: | Department of Psychological and Brain Sciences, The Johns Hopkins University, Baltimore, Maryland 21218, USA. h.crombag@sussex.ac.uk |
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Abstract: | Two experiments refined procedures to study Pavlovian influences on goal-directed behavior in mice and studied the effects of CS-US relations in Pavlovian-instrumental interactions. Independent groups of mice underwent Pavlovian training to associate either a 10-sec or 2-min auditory stimulus (CS) with reward. We next assessed the ability of the response-contingent CS presentations to reinforce novel instrumental responding (conditioned reinforcement; CRf) or the ability of noncontingent CS presentations to increase ongoing instrumental responding (Pavlovian-instrumental transfer; PIT). Whereas 10-sec training conditions produced strong CRf (and no PIT), 2-min training conditions produced robust PIT (but no CRf). |
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