Observations on regional cerebral blood flow in cortical and subcortical structures during language production in normal man |
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| Authors: | Claus-W. Wallesch Leif Henriksen Hans-H. Kornhuber Olaf B. Paulson |
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| Affiliation: | 1. Department of Neurology, Ulm University, Ulm, West Germany;2. Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark |
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| Abstract: | Regional cerebral blood flow (rCBF) was studied by single photon emission computerized tomography (SPECT) of inhaled xenon-133 in six normal volunteers during various language, articulatory, and control conditions. Language production increased rCBF in predominantly left-sided cortical and subcortical areas. The involved regions were anatomically related to a left frontal area (Broca's), to both caudate nuclei, to a left thalamic/pallidal area, and bilaterally in retrorolandic areas. The failure to demonstrate lateralized retrorolandic activity is thought to reflect the complexity of the tasks. |
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| Keywords: | Send correspondence and requests for reprints to Prof. Dr. O. B. Paulson Dept. of Neurology Rigshospitalet 9 Blegdamsvej DK-2100 Copenhagen Ø Denmark. |
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