不同性．别的非吸烟COPD患者肺功能和疾病严重程度的比较

比较不同性别的非吸烟的COPD患者的肺功能和疾病严重程度。选择承德医学院附属医院门诊就诊的非吸烟的稳定期COPD患者93例，其中男性34例，女性59例。对两组患者的肺通气功能和弥散功能，过去一年的急性加重次数、改良的呼吸困难评分及疾病严重程度进行比较。非吸烟的COPD患者男性组和女性组在FEVl％pred，FVC％pred，PEF％pred，FEF25—75％pred，FEF25％pred，FEF75％pred，DOSE评分方面比较，差异有统计学意义（P〈0．05）；在DL—CO％pred和Raw％pred方面比较，差异无统计学意义（P〉0．05）。非吸烟的女性COPD患者较男性COPD患者肺通气功能和小气道功能差，疾病严重程度重，可能与女性患者对生物燃料、空气污染等危险因素易感有关。

Comparison of Lung Function and Severity in Different Gender in Non-smoking Patients with COPD

To compare the lung function and severity in different genders in non-smoking patients with COPD. 93 COPD patients without smoking history were conducted in the department of respiratory disease in the affiliated hospital of Chengde Medical College, and were divided into 2 groups; male （n= 34）and female （n= 59）. We compared their lung function, frequency of exacerbation in the past year, scores of mMRC and disease severity. Between the male and female groups all FEV1% pred, FVC% pred, PEF% pred, FEF25 - 75 % pred, FEF25% pred, FEF75% pred and DOSE index scoring are signicantly difference （P〈0. 05）. But compared with DLCO% pred and Raw% pred there was no signicant difference （P〉0.05）. Female non-smokers COPD patients are worse than male non-srnokers patients in lung function and disease severity, it may be because that female are more sensitive to risk factors like biomass fuel and air pollution.