达标心率对缺血型心肌病和扩张型心肌病患者的影响

为观察达标心率对缺血型心肌病（ICM）和扩张型心肌病（DCM）患者预后的影响,所有入选ICM和DCM患者均给予常规抗心力衰竭药物及β受体阻滞剂（β-b）治疗,使心率维持于55次/分~60次/分,观察随访1年时的病死率、再入院率、舒张末期左室内径（LVEDd）、左室射血分数（LVEF）、氨基末端脑利钠肽前体（NT-proBNP）水平来评估二者的预后。结果显示,随访结束时ICM患者较DCM患者再入院率低（P=0.037）,LVEDd低（P=0.034）,LVEF高（P=0.028）,收缩压高（P=0.029）;对于ICM患者,随访结束时较出院时LVEDd低（P=0.047）,LVEF高（P=0.018）,收缩压高（P=0.042）。因此,心率达标对ICM患者有助于改善预后,对DCM患者改善不明显,ICM患者心率达标时获益更大。

The Influence of Standard Heart Rate on Patients with ICM and DCM

In order to observe the influence of standard heart rate on prognosis in patients with ICM and DCM,all the ICM and DCM patients were given regular anti-HF drugs andβ-blocher,keeping the heart rate at 55bpm~60bpm.By observing the mortality rate,readmission rate,left ventricular end-diastolic dimension（LVEDd）,left ventricular ejection fraction（LVEF）,N-terminal proBNP（NT-proBNP）after one year to evaluate their prognosis.The outcomes were that,at the end of follow-up,the ICM patients had lower readmission rate（P=0.037）,lower LVEDd（P=0.034）,higher LVEF（P=0.028）and higher systolic pressure（P=0.029）than DCM patients.As to the ICM patients at the end of follow-up,it had lower LVEDd（P=0.047）,higher LVEF（P=0.018）and higher systolic pressure（P=0.042）than discharged.So,as to ICM patients,standard heart rate was benefit to improving the prognosis,but it was not significant about DCM patients.The ICM patients had more profits than DCM patients.