地佐辛混合液对预防腭咽成形术苏醒期不良反应观察

比较应用芬太尼和地佐辛在预防腭咽成形术苏醒期，因疼痛以及口咽部呼吸道梗阻引起的患者躁动，恶心呕吐等不良反应情况，寻找最佳药物以及方法组合。200例美国麻醉师协会（ASA）分级I级～Ⅱ级患者，随机分为A、B、C、D四组，给药时间均为手术结束前15分钟，A组：单次静注芬太尼0．1μg·kg^-1；B组单次静注地佐辛0．1mg·kg^-1；C组单次静注地佐辛0．1mg·kg^-1＋氟哌利多2．5mg；D组单次静注地佐辛0．1mg·kg^-1＋氟哌利多2．5mg＋伤口涂抹复方利多卡因乳膏。记录患者苏醒时间，拔管后呼吸抑制，恶心呕吐等情况。结果D组出现恶心呕吐、头痛头晕例数明显少于A、B、C三组（P〈o．05）。手术结束前15分钟单次静注地佐辛O．1mg·kg^-1＋氟哌利多2．5mg＋伤口涂抹复方利多卡因乳膏，对于有效预防腭咽成形术苏醒期疼痛、恶心呕吐、头痛以及躁动是有效的。

Observe of Adverse Reactions about Dezocine Mixture on the Prevention Uvulopalatopharyngoplasty Surgery Recovery Period

To compare the application of fentanyl, the dezocine in preventing uvulopalatopharyngoplasty recovery period, patients with oropharyngeal airway obstruction and pain caused by restlessness, nausea, vomiting and other adverse reactions, to find the best combination of drugs and methods. 200 cases of ASA Ⅰ ~ Ⅱ grade were randomly assigned to the four groups A B C D, 15 minutes before the end of surgery the four groups A B C D are administ, Group A： intravenous injection of Fentanyl 0. 1μg· kg^-1 ; Group B： intravenous injection of Dezocine 0. 1μg· kg^-1 ; Group C： intravenous injection of the dezocine 0.1mg·kg^-1＋ Droperidol 2.5 mg; group D： intravenous injection of the Dezocine 0. 1mg·kg^-＋ Droperidol 2. 5mg ＋ wound smear Lidocaine cream. Record patient recovery time, after extubation respiratory depression, nausea, vomiting and so on. group D, nausea, vomiting, headache, dizziness, significantly less than the number of eases of A, B, C three groups （P〈0.05）. 15 minutes before the end of surgery to intravenous Dezocine 0.1lmg·kg^-1 ＋ Droperidol 2. 5mg ＋ wound smear Lidocaine cream, for effective prevention of uvulopaiatopharyngoplasty recovery period pain, nausea, vomiting, headache and restlessness are effective.