| 关于实验动物运动模型建立的伦理思考 |
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| 引用本文： | 肖楚兰, 陈娇娇, 郭冰洁, 殷子斐, 常运立, 李柏. 关于实验动物运动模型建立的伦理思考[J]. 医学与哲学, 2022, 43(2): 38-42. doi: 10.12014/j.issn.1002-0772.2022.02.08 |
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| 作者姓名： | 肖楚兰 陈娇娇 郭冰洁 殷子斐 常运立 李柏 |
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| 作者单位： | ①. 海军军医大学第一附属医院康复科 上海 200433; ②. 海军军医大学中医系 上海 200433; ③. 海军军医大学基础医学院 上海 200433 |
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| 基金项目： | 2019年海军军医大学第一附属医院青年启动基金项目(2019QNB05) |
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| 摘 要： | 基于目前广泛应用的动物实验伦理3R和5F原则，通过深入分析已有运动干预文献中的动物运动模型构建方法，分别就运动模型建立前实验动物的选取，运动模式、运动剂量的确定，模型建立过程中不同阶段不同运动形式所涉及的伦理问题，以及实验动物安乐死等各个方面进行伦理分析，探讨伦理关怀在动物运动模型建立中的必要性和重要性。运动模型的构建作为研究运动干预的关键环节是极其重要的，此建立过程中涉及到诸多动物实验伦理问题。
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| 关 键 词： | 动物模型 伦理关怀 医学伦理 动物福利 |
| 收稿时间： | 2021-05-08 |
| 修稿时间： | 2022-01-05 |
Ethical Reflection on the Establishment of Exercise Models of Experimental Animals |
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| XIAO Chu-lan, CHEN Jiao-jiao, GUO Bing-jie, YIN Zi-fei, CHANG Yun-li, LI Bai. Ethical Reflection on the Establishment of Exercise Models of Experimental Animals[J]. Medicine & Philosophy, 2022, 43(2): 38-42. doi: 10.12014/j.issn.1002-0772.2022.02.08 |
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| Authors: | XIAO Chu-lan CHEN Jiao-jiao GUO Bing-jie YIN Zi-fei CHANG Yun-li LI Bai |
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| Affiliation: | ①. Department of Rehabilitation, The First Affiliated Hospital, Naval Medical University, Shanghai 200433, China |
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| Abstract: | Based on the widely used experimental animal ethical principle of 3R and 5F, analyzing the establishment of animal exercise model in current exercise intervention literature, this paper presents ethical analysis on the ethical problems involved in experimental animal selection before modeling, exercise amount, different exercise forms in different stages of model establishment, and the experimental animal euthanasia, in order to explore the necessity and importance of ethical care in animal exercise model establishment. Exercise model establishment is a key link in exercise intervention research, which involves some ethical issues in animal experiments. |
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| Keywords: | animal model ethical care medical ethics animal welfare |
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