The role of the study section in the NIH peer review system

This paper describes the NIH grants review system, which is designed to evaluate a grant proposal for both technical merit and programmatic interest. In particular, it discusses the initial review for scientific and technical merit, using as example the Computer Study Section, which reviews applications in computer science, physiological modeling, and statistics. Criteria for evaluation include: knowledge of the state of the field, relevance to scientific innovation, commitment by the investigator, strength of association between theoretician and practitioner, methodology, human factors, and experience.