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Predictors of Improvement in Pediatric Chronic Migraine: Results from the Cognitive-Behavioral Therapy and Amitriptyline Trial |
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| Authors: | Rettig Eman K. Ergun Gokce Warfield Janeece R. Slater Shalonda K. LeCates Susan L. Kabbouche Marielle A. Kacperski Joanne Hershey Andrew D. Powers Scott W. |
| Affiliation: | 1.School of Professional Psychology, Wright State University, Dayton, OH, USA ;2.Division of Behavioral Medicine & Clinical Psychology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA ;3.Division of Neurology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA ;4.Headache Center, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA ;5.Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA ;6.8967 Charleston View Drive, Mason, OH, 45040, USA ;7.110 C Health Sciences Building, 3640 Colonel Glenn Highway, Dayton, OH, 45435, USA ;8.9 North Edwin C. Moses Blvd., Dayton, OH, 45402, USA ;9.9560 Children’s Drive, Mason, OH, 45040, USA ; |
| Abstract: | Explore predictors of improvement in headache days and migraine-related disability through a secondary analysis of the cognitive-behavioral therapy plus amitriptyline trial in children and adolescents (Clinical Trials Registration Number: NCT00389038). Participants were 135 youth aged 10–17 years old diagnosed with chronic migraine. Predictor variables included group assignment (treatment or control), baseline scores from depression and quality of life measures, and demographic variables. Criterion variables included headache days and migraine-related disability. Higher baseline depression scores were indicative of more days with headache post-treatment regardless of group assignment. Family income at the higher-end of the low-income range was significantly associated with less migraine-related disability regardless of group assignment (Household Income: HINC-01 in The United States Census Bureau. Bureau, U, 2020). Results from this secondary analysis identify depression symptoms and family income as predictors that can impact headache frequency and migraine-related disability. Self-reported symptoms of depression and family income are important factors to consider as part of the biopsychosocial model of care. |
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