A technique for chronic recording of systemic arterial blood pressure in the unrestrained rat |
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| Authors: | Leo B DiCara Bruce A Pappas Fay Pointer |
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| Institution: | 1. Albert Einstein College of Medicine, Eastchester Road and Morris Park Avenue, 10461, Bronx, New York
2. The Rockefeller University, 10021, New York, New York
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| Abstract: | A technique is described for the chronic recording of systematic arterial blood pressure, respiration, and heart rate in the unrestrained rat. The surgical implantation and anchoring procedures described are compatible with the delivery of noxious electric shock and/or rewarding intracranial brain stimulation as reinforcement. Data on catheter patency are analyzed in 65 rats participating in a variety of experiments on the instrumental and classical conditioning of blood pressure responses. The results indicate that it is difficult to maintain satisfactory catheter performance beyond 2 weeks. |
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