Behavioral test systems in marmoset monkeys |
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| Authors: | I H C H M Philippens B P C Melchers T A P Roeling P L B Bruijnzeel |
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| Institution: | (1) Department of Diagnosis and Therapy, TNO Defence, Security and Safety, Lange Kleiweg 137, 2288 GJ Rijswijk, The Netherlands;(2) Department of Psychopharmacology, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, Sorbonnelaan 16, 3584 CA Utrecht, The Netherlands |
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| Abstract: | A number of neurobehavioral methods have been developed to test behavior in marmoset monkeys. These test systems are (1) the bungalow test, which quantifies spontaneous explorative behavior, (2) the hand-eye coordination test, which tests a learned task of coordinated motor behavior, and (3) the fear-potentiated startle response, which tests and quantifies pathological anxiety manifested by a response of fright. The test systems are extensively discussed, and the value of these test systems is exemplified by applying them to neurological disorders to register disease activity and drug efficacy. |
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