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Confirmation of an Inhibitory Control Deficit in Attention-Deficit/Hyperactivity Disorder
Authors:Russell Schachar  Victor L. Mota  Gordon D. Logan  Rosemary Tannock  Paula Klim
Affiliation:(1) Department of Psychiatry and the Brain and Behavior Program, The Hospital for Sick Children and the University of Toronto, Toronto, Ontario, Canada;(2) Department of Child Psychiatry, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.;(3) Department of Psychology, University of Illinois, Champaign, Illinois
Abstract:The objective of this study was to determine whether deficient inhibitory control distinguishes children with a diagnosis of attention-deficit/hyperactivity (ADHD) disorder, conduct disorder (CD), and comorbid ADHD + CD from normally developing children. Participants were rigorously diagnosed children (age 7 to 12 years) with ADHD (N = 72), CD (N = 13) or ADHD + CD (N = 47) and 33 control children (NC). We studied inhibitory control using the stop-signal paradigm, a laboratory task that assessed the ability to inhibit an ongoing action. The ADHD group had significantly impaired inhibitory control compared to NC, CD, and ADHD + CD children. These results indicate that children with ADHD have deficient inhibition as measured in the stop-signal paradigm and that ADHD occurring in the presence of ADHD + CD may represent a phenocopy of CD rather than a variant of ADHD.
Keywords:Attention deficit hyperactivity disorder  conduct disorder  comorbidity  inhibition
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