A method of determining unbiased distribution in the latin square

The paper describes a method of constructing Latin-square designs in which treatment sequences are unbiased with regard to serial order as well as position of treatment. The procedure is useful for those Latin squares in which the number of cells in each column (or row) is an even number, which, when written in ascending and descending series, contain corresponding ordered numbers prime to each other. Such numbers are 2, 4, 6, 10, 12, 16, 18, 22, 28, 30, 36, etc.