A microprocessor control system and solid state interface for controlling electrophysiological studies of conditioning

This paper describes a microprocessor control system and solid state interface for controlling the apparatus in combined behavioral-electrophysiological studies of conditioning. The computer program, which is designed to control classical conditioning of the rabbit’s nictitating membrane response, provides the flexibility to control all conditioning parameters (e.g., interstimulus and intertrial intervals, trial type, and sequence of trial types) with only minor modifications. The system is free from artifacts that can distort electrophysiological recordings and can easily be modified to accommodate other behavioral paradigms in which electrophysiological responses are recorded.