抑郁症神经成像研究的临床转化:预防、诊断和治疗的新取向

抑郁症的预防、诊断和治疗是临床所面临的主要问题,其效果的提升有待超越传统方法,寻求新的方法和技术。其中抑郁症的神经成像转化研究为此提供了一个新的突破口,该研究取向旨在将抑郁症的神经成像基础研究的发现转化为临床运用。文章综述了其在抑郁症的预防、诊断和治疗上的潜在运用价值。未来方向需要更好地促进抑郁症神经成像转化研究的双向自由流通、强调将新的方法转化到日常的临床实践和健康决策上去、促进多学科的合作和相关人才的培养,以及进一步探究转化过程中所面临的特定基础和临床主题。

Clinical Translation of Neuroimaging Research in Depression: A New Approach to Prevention, Diagnosis and Treatment of Depression

Prevention, diagnosis and treatment of depression are main clinical challenges. The improvements in these fields are anticipated when new methods and techniques transcend traditional ones. The neuroimaging approach applied to translational research in depression provides a new breakthrough for achieving such aim, which refers to translate the neuroimage basic findings into clinical applications. The paper reviewed its latest findings and potential application value in the prevention, diagnosis and treatment of depression. Future directions are aimed at enhancing bidirectional transmission, placing more emphasis on turning innovations into everyday clinical practice and health decision-making, improving multidisciplinary cooperation and personal training, and requiring further research on specific topics during translational process.