Anterior cingulate cortex in schema assimilation and expression |
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Authors: | Szu-Han Wang Dorothy Tse Richard G M Morris |
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Affiliation: | Centre for Cognitive and Neural Systems, The University of Edinburgh, EH8 9JZ Edinburgh, United Kingdom. s.wang@ed.ac.uk |
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Abstract: | In humans and in animals, mental schemas can store information within an associative framework that enables rapid and efficient assimilation of new information. Using a hippocampal-dependent paired-associate task, we now report that the anterior cingulate cortex is part of a neocortical network of schema storage with NMDA receptor-mediated transmission critical for information updating, and AMPA receptor-mediated transmission required for the expression and updating of stored information. |
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