外科手术抗生素的预防性应用探讨

手术野感染(surgical site infection,SSI)是外科手术的并发症之一,预防性抗生素使用可减少SSI发生率,但使用的目的与作用仅仅是在手术过程中,一旦手术结束这一作用也就结束。对于创伤较小清洁手术可以不用预防性抗生素;轻度污染手术创伤不大,也可以不使用预防性抗生素;只有患者存在高危因素时才考虑应用。麻醉诱导期使用最为合理的。对不同的手术部位和不同的创伤程度,应选择不同的抗生素即个体化给药原则。

Antibiotic Prophylaxis in Surgery

Surgical site infection(SSI) is one of complications in surgery, antibiotic prophylaxis can decrease SSI, but the purpose and the function merely aims at the course of operation, once operation is over, the function of prophylaxis is not in significance. Antibiotic prophylaxis is unnecessary in no-contaminated or lightly contaminated minus surgical trauma, only for those with easy-infected patients. Antibiotic prophylaxis application is reasonable in the induction of anesthesia. It should be in individual principle according to different site of surgery and different trauma.