| 血清S-CD105监测乳腺癌术后复发转移的意义 |
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| 引用本文： | 范立壮,范忠林,李云涛,马力,李艳. 血清S-CD105监测乳腺癌术后复发转移的意义[J]. 医学与哲学(人文社会医学版), 2010, 0(12): 52-53 |
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| 作者姓名： | 范立壮 范忠林 李云涛 马力 李艳 |
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| 作者单位： | [1]河北省保定市第二医院普外科,河北保定071000 [2]河北医科大学第四医院乳腺中心／河北省乳腺疾病诊治中心,河北石家庄050011 [3]中国人民解放军第二五二医院妇产科,河北保定071000 |
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| 基金项目： | 基金项目：河北省普通高校强势特色学科资助项目,项目编号：（2005）52号 |
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| 摘 要： | 探讨复发转移性乳腺癌患者血清S-CD105表达情况及其临床意义。用酶联免疫吸附实验(ELISA)检测50例复发转移性乳腺癌,20例乳腺良性疾病及15例健康女性血清S-CD105的浓度;用微粒子化学发光法检测复发转移患者同期血清CEA、CA15-3的浓度。复发转移性乳腺癌患者血清S-CD105表达明显升高。单项检测S-CD105优于CEA、CA15-3,与CEA和CA15-3联合检测表达相似。血清S-CD105可能对监测乳腺癌患者术后复发转移有重要临床价值。
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| 关 键 词： | 乳腺肿瘤 CD105 复发 转移 血清 |
Clinical Significance of Serum S--CD105 Level of Patients with Postoperative Recurrent and Metastatic Breast Cance |
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| Affiliation: | r FAN Li-zhuang, FAN Zhong-lin, LI Yun tao, et al. Department of Surgery ,Second Hospital of Baoding Hebei Province , Baoding 071000, China |
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| Abstract: | To explore the levels and clinical significance of serum S--CD105 of patients with postoperative recurrent and me tastatic breast cancer. Serum S--CD105 of 50 postoperative patients with recurrent and metastatic breast cancer, 20 patients with breast benign disease, and 15 healthy controls was detected by ELISA. CEA, CA15--3 of the same patients were measured by micropartiele chemilumin--escence immunoassay in corresponding period. The serum S--CD105 levels of the patients with postoperative recurrent and metastatic breast cancer rise up obviously. The positive rate of serum S-CD105 is higher than CEA, CA15-3 as a signal marker, but has no difference with combining test of CEA and CA15-3. It is expected to he a marker for the diagnosis of recurrence and metastasis of breast cancer. |
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| Keywords: | breast neoplasm CD105 recurrence metastasis serum |
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