Perceived behavioral changes in early multiple sclerosis |
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| Authors: | Lima Fabiana Souza Simioni Samanta Bruggimann Laure Ruffieux Christiane Dudler Jean Felley Christian Michetti Pierre Annoni Jean-Marie Schluep Myriam |
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| Institution: | Department of Neurology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland. |
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| Abstract: | Acquired behavioral changes have essentially been described in advanced multiple sclerosis (MS). The present study was designed to determine whether behavioral modifications specifically related to the MS pathological process could be identified in the initial phase of the disease, as compared to control patients with chronic, relapsing and progressive inflammatory disorders not involving the central nervous system (CNS). Eighty-eight early MS patients (Expanded Disability Status Scale score
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