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Developmental dissociation of visual dorsal stream parvo and magnocellular representations and the functional impact of negative retinotopic BOLD responses
Authors:Isabel Catarina Duarte,Gil Cunha,Joã  o Castelhano,Francisco Sales,Aldina Reis,Joã  o Paulo Silva Cunha,Miguel Castelo-Branco
Affiliation:1. Brain Imaging Network, ICNAS, Azinhaga de Santa Comba, 3000-058 Coimbra, Portugal;2. Institute for Biomedical Imaging and Life Sciences, IBILI, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal;3. Coimbra University Hospital, Praceta Prof. Mota Pinto, 3000-075 Coimbra, Portugal;4. INESC TEC / Dep. of Electrical and Computer Engineering, Faculty of Engineering, University of Porto, 4200-465 Porto, Portugal
Abstract:Localized neurodevelopmental defects provide an opportunity to study structure–function correlations in the human nervous system. This unique multimodal case report of epileptogenic dysplasia in the visual cortex allowed exploring visual function across distinct pathways in retinotopic regions and the dorsal stream, in relation to fMRI retinotopic mapping and spike triggered BOLD responses.
Keywords:fMRI retinotopic mapping   Visual function   EEG/fMRI   Dorsal stream   Magnocellular pathway   Negative BOLD
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