| 急性重症胰腺炎的抗生素治疗策略 |
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| 引用本文： | 李兴睿 陈孝平. 急性重症胰腺炎的抗生素治疗策略[J]. 医学与哲学(人文社会医学版), 2006, 27(11): 12-14 |
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| 作者姓名： | 李兴睿 陈孝平 |
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| 作者单位： | 华中科技大学同济医学院同济医院普通外科 湖北武汉430030 |
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| 摘 要： | 继发性感染是导致急性重症胰腺炎(severe acute pancreatitis,SAP)高病死率最重要的因素。继发感染的微生物多为革兰阴性菌。选用抗菌药物需兼顾病原菌敏感性及抗菌药物穿透血胰屏障能力,合理选择用药方式;对于CT证实有胰腺坏死的急性重症胰腺炎,可预防性使用抗生素;氟康唑可作为经验性抗真菌治疗的首选药物。
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| 关 键 词： | 急性重症胰腺炎 抗生素 治疗 |
| 文章编号： | 1002-0772（2006）11-0012-03 |
| 收稿时间： | 2006-11-20 |
| 修稿时间： | 2006-11-20 |
The Application of Antibiotics in Severe Acute Pancreatitis |
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| LI Xing-ri , CHEN Xiao-ping.. The Application of Antibiotics in Severe Acute Pancreatitis[J]. Medicine & Philosophy:Humanistic & Social Medicine Edition, 2006, 27(11): 12-14 |
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| Authors: | LI Xing-ri CHEN Xiao-ping. |
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| Affiliation: | Department of General Surgery, Tongji Hospital Medical College, Huazhong University of Science and Techonology , Wuhan 430030, China |
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| Abstract: | Secondary infection is the most important factor of high mortality in the patients with severe acute pancreatitis(SAP). Gram-negative bacteria are the most common microorganism of secondary infection. Sensitivity of bacteria to antibiotics and the ability of antibiotics to go through blood-pancreas are two important factors to choose antibiotics. Prophylactic antibiotics can be used in the patients with pancreas necrosis confirmed by CT. Fluconazole can be used as the first choice to treat fungi infection in SAP. |
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| Keywords: | severe acute pancreatitis antibiotics treatment |
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