溃疡性结肠炎的血清学诊断

对溃疡性结肠炎（UC）的诊断应结合临床表现、内镜、实验室、放射学及病理学检查等。血清学标志物在鉴别UC和克罗恩病中有一定价值，包括核周型抗中性粒细胞抗体、抗酿酒酵母抗体、抗胰腺腺泡抗体、抗细胞外膜蛋白复合物抗体和抗12抗体等。这些抗体的检测对UC的诊断和鉴别诊断、活动度判定、亚型分层以及对治疗的反应方面有重要价值。

Serological Markers in the Diagnosis of Ulcerative Colitis

Diagnosis for ulcerative colitis （UC） includes clinical significances, endoscopic findings, laboratory tests, radiological and histological changes. Serological markers play an important role in differentiating diagnosis from Crohn＇s disease and include anti--neutrophil cytoplasmic antibody, anti--sacchromyces cerevisia antibody, antibodies for exocrine pancreas and Escherichia coli outer membrane porin C, and anti-I2 antibody. These antibodies are useful in having the diagnosis and differentiating diagnosis of UC, evaluating the activities and classification of disease, and predicting the treatment in the clinic.