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Update and Review: Maternal Serum Screening
Authors:Kelly E. Ormond
Affiliation:(1) Department of Pediatrics, University of Vermont College of Medicine, Burlington, Vermont;(2) Northwestern Memorial Hospital, Chicago, Illinois, 60611
Abstract:Maternal serum levels of alpha fetoprotein (AFP), human chorionic gonadotropin (hCG), and unconjugated estriol (uE3) can be used to screen pregnancies for neural tube defects, Down syndrome, Trisomy 18, and pregnancy complications. This article summarizes the most recent information regarding maternal serum screening, including genetic counseling issues.
Keywords:maternal serum screening  alpha-fetoprotein
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