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A Meta-Analysis of Working Memory Impairments in Autism Spectrum Disorders
Authors:Ya Wang  Yi-bing Zhang  Lu-lu Liu  Ji-fang Cui  Jing Wang  David H. K. Shum  Therese van Amelsvoort  Raymond C. K. Chan
Affiliation:1.Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health,Institute of Psychology,Beijing,China;2.Institute of Psychology, Chinese Academy of Sciences,Beijing,China;3.Department of Youth Work,China Youth University for Political Sciences,Beijing,China;4.University of Chinese Academy of Sciences,Beijing,China;5.National Institute of Education Sciences,Beijing,China;6.Menzies Health Institute Queensland and School of Applied Psychology,Griffith University,Gold Coast,Australia;7.Department of Psychiatry and Psychology,Maastricht University,Maastricht,The Netherlands
Abstract:Autism spectrum disorders (ASD) are characterized by executive dysfunction, and working memory (WM) comprises one core component of executive function. Many studies have investigated WM impairments in individuals with ASD, however, a conclusive agreement has not been reached. The present study provided a meta-analytic review of WM impairments in individuals with ASD and evaluated potential moderating variables of this problem. Twenty-eight studies were included in this study, and the participants comprised 819 individuals with ASD and 875 healthy controls. A significant WM impairment (Cohen’s d?=??0.61) was identified in the individuals with ASD, however, this impairment was not associated with age. Results of moderation analyses showed that (a) spatial WM was more severely impaired than verbal WM and (b) the component of cognitive processing (maintenance vs. maintenance plus manipulation) did not affect the severity of WM impairments. These findings suggest that WM is impaired in individuals with ASD and may have implications for interventions related to WM impairments in these individuals.
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