Sex differences in functional cerebral asymmetries in a repeated measures design

The aim of the present study was to analyze whether task repetitions which are an inevitable part of repeated measures designs might induce performance alterations specific for gender and hemisphere. Male and female subjects conducted twice a lexical decision, a polygon recognition, and a face discrimination task as a visual half field paradigm with the two experimental sessions repeated by 2 weeks. The results show that only in female subjects can a session effect for the lexical decision and the polygon recognition task be demonstrated which is hemisphere specific. Thus, repeated measures designs seem to have a gender- and hemisphere-specific effects of their own which could confound with other variables under study.