Influence of a 14-day regimen of electrical stimulation involving large portions of the cerebral mass on later habit acquisition in the rat

Four groups of rats, one of which served as a normal, nonoperated group, were used. The other three groups were operated and fitted with an electrode carrier of eight electrodes of varying lengths arranged in a 7.5 mm X 5 mm rectangle. About 10 or 12 days after surgery, the following groups of animals underwent a 14-day regimen wherein each animal spent 15 min in a deep, metal, electrically insulated cylinder: Group A, normal, nonoperated group, with no intervention; Group B, stimulated each day with 45 trains of rectangular biphasic pulses (3 trains per min) at the rate of 20 pulses per second (pps); Group C, the same but at the rate of 100 pps; Group D, the same but 180 pps. After a 48-hr fast and without benefit of shaping, each animal was placed for 60 min in a lever-pressing device and was rewarded with a pellet after each three to four presses. The resulting performance curves showed no improvement in pressing rate for Group A; marginal improvement for Group B; definite improvement for Group C; and the greatest improvement for Group D, the terminal rate being almost twice that of Group C.