A case of thalamic aphasia with postmortem verification |
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| Authors: | Bruce Crosson Jerry C. Parker Albert K. Kim Reg Lawrence Warren John J. Kepes Richard Tully |
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| Affiliation: | 1. Department of Neurology, Cork University Hospital, Ireland;2. Department of Neurology, Medical University Innsbruck, Austria;3. University College Cork, Ireland;1. Department of Basic Medical Science, Neuroscience, and Sense Organs, University of Bari ‘Aldo Moro’, Piazza Giulio Cesare 11, 70124 Bari, Italy;2. National Institute of Nuclear of Physics-Branch of Bari, Via E. Orabona 4, 70125 Bari, Italy;3. Interuniversity Department of Physics ‘M. Merlin’, University of Bari ‘Aldo Moro’, Via E. Orabona 4, 70125 Bari, Italy;4. Psychiatry Unit, Bari University Hospital, Piazza Giulio Cesare 11, 70124, Bari, Italy;5. IRCCS “Casa Sollievo della Sofferenza”, Viale Cappuccini, 1, I-71013 San Giovanni Rotondo, Italy |
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| Abstract: | This study discusses a case of aphasia after dominant thalamic lesion, a hemorrhagic infarction. Unlike other such cases, both repeated standardized assessment and postmortem verification were available. The patient was assessed at 3 weeks and again at 9 weeks postonset. The aphasia demonstrated the syndrome common to dominant thalamic hemorrhage: fluent but paraphasic output sometimes deteriorating to jargon, comprehension less impaired than this type of output usually indicates, and the least impairment in repetition. As sometimes reported in previous cases, semantic paraphasias were more common than phonemic paraphasias. The lesion was located in the dorsal aspect of the lateral nucleus, but it extended into the pulvinar, including the anterior superior lateral aspect which has been implicated in language by previous studies. Thus, data from this case are consistent with an involvement of the dominant pulvinar in language and suggest that this role involves the semantic aspects of language. |
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