Perceptual hysteresis as a marker of perceptual inflexibility in schizophrenia |
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| Affiliation: | 1. Université Paris VI (UPMC), Paris, France;2. Institut Jean Nicod (IJN), UMR 8129 (CNRS, ENS, EHESS), Paris, France;3. Laboratoire de Neurosciences Cognitives (LNC), U960 (INSERM, CNRS, ENS), Paris, France;4. Laboratoire des Systèmes Perceptifs (LSP), UMR 8248 (CNRS, ENS), Paris, France;5. Department of Psychiatry, St-Antoine Hospital, AP-HP, Paris, France;6. École des Hautes Études en Sciences Sociales, Paris, France;7. Service Universitaire de Réhabilitation, Centre de Réhabilitation, Centre Hospitalier Le Vinatier, Lyon, France;8. Centre de Neurosciences Cognitives (CNC), UMR 5229 (CNRS), Bron Cedex, France;1. Department of Psychology, University of North Texas, 1155 Union Circle #311280, Denton, TX 76203, USA;2. Department of Psychiatry and Behavioral Sciences, Stony Brook University, USA;3. Department of Psychology, University of Notre Dame, USA;1. Behavioural Science Institute, Radboud University Nijmegen, the Netherlands;2. GGZ Breburg, Tilburg, the Netherlands;3. Centre for Emotional Health, Macquarie University, Sydney, Australia;4. University of Amsterdam, the Netherlands;1. Helmholtz–Institut für Strahlen– und Kernphysik, Universität Bonn, Germany;2. National Research Centre “Kurchatov Institute”, Petersburg Nuclear Physics Institute, Gatchina, Russia;3. Physikalisches Institut, Universität Bonn, Germany;4. Institut für Experimentalphysik I, Ruhr–Universität Bochum, Germany;5. II. Physikalisches Institut, Universität Gießen, Germany;6. Physikalisches Institut, Universität Basel, Switzerland;7. Department of Physics, Florida State University, Tallahassee, FL 32306, USA;1. School of Resources and Environmental Engineering, Hefei University of Technology, Hefei 230009, China;2. Department of Biosystems Engineering, Auburn University, Auburn, AL 36849, USA;3. Center for Bioenergy and Bioproducts, Auburn University, Auburn, AL 36849, USA;1. University of Bremen, Institute of Psychology and Cognition Research, Bremen, Germany;2. Centre for Cognitive Science, Bremen, Germany;3. Experimental Psychology Lab, Dpt. of Psychology, European Medical School, University of Oldenburg, Germany;4. Research Center Neurosensory Science, University of Oldenburg, Germany |
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| Abstract: | People with schizophrenia are known to exhibit difficulties in the updating of their current belief states even in the light of disconfirmatory evidence. In the present study we tested the hypothesis that people with schizophrenia could also manifest perceptual inflexibility, or difficulties in the updating of their current sensory states. The presence of perceptual inflexibility might contribute both to the patients’ altered perception of reality and the formation of some delusions as well as to their social cognition deficits. Here, we addressed this issue with a protocol of auditory hysteresis, a direct measure of sensory persistence, on a population of stabilized antipsychotic-treated schizophrenia patients and a sample of control subjects. Trials consisted of emotional signals (i.e., screams) and neutral signals (i.e., spectrally-rotated versions of the emotional stimuli) progressively emerging from white noise – Ascending Sequences – or progressively fading away in white noise – Descending Sequences. Results showed that patients presented significantly stronger hysteresis effects than control subjects, as evidenced by a higher rate of perceptual reports in Descending Sequences. The present study thus provides direct evidence of perceptual inflexibility in schizophrenia. |
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| Keywords: | Schizophrenia Perceptual inflexibility Belief inflexibility Perceptual hysteresis Predictive deficits |
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