Multivariate multiple regression analyses: a permutation method for linear models

A multivariate extension of a univariate procedure for the analysis of experimental designs is presented. A Euclidean-distance permutation procedure is used to evaluate multivariate residuals obtained from a regression algorithm, also based on Euclidean distances. Applications include various completely randomized and randomized block experimental designs such as one-way, Latin square, factorial, nested, and split-plot designs, with and without covariates. Unlike parametric procedures, the only required assumption is the randomization of subjects to treatments.