The brain and sodium homeostasis

Sodium homeostasis continues to be one of the principal areas of intense investigation in humoral physiology. This is not only because of its central role in major medical problems such as hypertension and edema. It also follows from the many intriguing problems of adaptations involving sodium control by animal species in the course of phylogenetic emergence from the oceans and irradiation into diverse ecological niches of terrestrial existence. Many of the central problems of this wide field of inquiry remain unsolved.