Alcohol: Effects on Neurobehavioral Functions and the Brain |
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Authors: | Marlene Oscar-Berman Ksenija Marinković |
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Affiliation: | (1) Departments of Anatomy and Neurobiology, Psychiatry, and Neurology, Boston University School of Medicine, L-815, 715 Albany Street, Boston, MA 02118, USA;(2) Psychology Research Service, VA Healthcare System, Boston Campus, Boston, MA, USA;(3) Radiology Department, Harvard Medical School, Boston, MA, USA;(4) Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, USA |
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Abstract: | Alcoholism results from an interplay between genetic and environmental factors, and is linked to brain defects and associated cognitive, emotional, and behavioral impairments. A confluence of findings from neuroimaging, physiological, neuropathological, and neuropsychological studies of alcoholics indicate that the frontal lobes, limbic system, and cerebellum are particularly vulnerable to damage and dysfunction. An integrative approach employing a variety of neuroscientific technologies is essential for recognizing the interconnectivity of the different functional systems affected by alcoholism. In that way, relevant experimental techniques can be applied to assist in determining the degree to which abstinence and treatment contribute to the reversal of atrophy and dysfunction. |
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Keywords: | Alcoholism Frontal lobes Limbic system Cerebellum Right hemisphere |
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