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用现代医学理论阐明阴虚证的本质和发病学机理
引用本文:申维玺,孙燕,刘晓燕,刘玉梅. 用现代医学理论阐明阴虚证的本质和发病学机理[J]. 医学与哲学(人文社会医学版), 2005, 0(13)
作者姓名:申维玺  孙燕  刘晓燕  刘玉梅
作者单位:广州医学院广州市肿瘤医院 广东广州510095(申维玺,刘晓燕,刘玉梅),中国医学科学院肿瘤医院 北京100021(孙燕)
基金项目:科技部重大基础研究前期计划(2004CCC00200),国家自然科学基金项目(项目编号C30450008)
摘    要:用现代医学理论阐明阴虚证的本质具有重大科学意义,但我国半个世纪的研究未能取得根本突破。用现代医学理论阐述了阴虚证的本质和发病学机理,即阴虚证的本质是细胞因子,其发病学机理是由于机体在各种致病因素的作用下,白细胞介素1和肿瘤坏死因子等炎性细胞因子基因的表达水平增强、生物学活性相对升高,引起细胞因子网络紊乱的结果。

关 键 词:阴虚证  本质  细胞因子  理论研究

Investigate the Essence and Pathogenesis of Yin-deficiency Syndrome with Modern Medical Theory
SHEN Wei-xi,SUN Yan,LIU Xiao-yan,et al.. Investigate the Essence and Pathogenesis of Yin-deficiency Syndrome with Modern Medical Theory[J]. Medicine & Philosophy:Humanistic & Social Medicine Edition, 2005, 0(13)
Authors:SHEN Wei-xi  SUN Yan  LIU Xiao-yan  et al.
Affiliation:SHEN Wei-xi,SUN Yan,LIU Xiao-yan,et al.Guangzhou Cancer Hospital,Guangzhou Medical College,Guangzhou 510095,China
Abstract:It has a great significance to clarify the essence of syndromes of Traditional Chinese Medicine with modern medical theory. But there has not been any breakthrough in the field for half a century. The essence and pathogenesis of Yin-deficiency syndrome was investigated with modern medical theory here. The essence of Yin-deficiency syndrome is cytokines and the pathogenesis of Yin-deficiency syndrome is due to the disequilibrium status resulted from the relative increase of the biological activity of pro-inflammatory cytokines like interleukin-1, tumor necrosis factor, etc.
Keywords:Yin-deficiency syndrome  essence  cytokines  theory research
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