关于结直肠患者的PCQ风险评分系统的运用进展

摘要：回顾关于结直肠患者的PCQ（patient consultation questionnaire，问卷量表一加权评分系统）风险评估体系自1999年产生以来的运用进展情况。查阅了1999年至今的相关文献，分析总结PCQ系统的评估原理、评估流程、评估效果，并作一综述。结果显示：PCQ系统对各种疾病的分辨能力较高，随着WNS（weighed numerical score，加权分数）分数的增加，各种疾病分数表现为阶梯状上升的层级分布图。癌症患者与非癌症患者的平均WNS分剐是70-80、40-55之间，有统计学意义。当以WNS分数60为界时，WNS系统的敏感度、特异度可分别达到86.5％、84.5％。以WNS50为转诊标准，仅40％的患者需紧急转诊，发现91％的癌症患者。提示PCQ系统的准确性高、特异性强，是一个很有发展前景的评估体系，可以进一步的开展多中心研究进行验证，进而推广使用并引进到中国。

Advances in PCQ Risk Evaluative System of Colorectal Cancer

Review the development of exertion on PCQ hazard graded system in eolorectal patients. The irrelative literatures had been retrieved from 1999 up to present in order to analyze and summarize the elements, program and effect of evaluation of PCQ system. The PCQ system provided a high discrimination between diseases. With the increasing of WNS, the diseases presented a ladder-like distribution. WNS of cancer patients and non-cancer patients were 70-80 and 40-45, which has a statistical significance. At a cut-off of the WNS of 60, the sensitivity and specificity reach ed 86.5% and 84.5%, respectively. At a cut-off of 50, we would need to screen 40% of the referred population to detect 91% of the cancers. Therefore,the degrees of veracity, specificity and sensitivity are so high that the PCQ system is an evaluation system that has optimistic foreground. We can develop further multi-center trial to prove and expand it into China.