Negative Interpretation Biases Precede the Onset of Psychosis |
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| Institution: | King’s College London;King’s College London;King’s College London;King’s College London;Department of Psychiatry & Psychotherapy, Philipps-University Marburg, Germany;King’s College London;King’s College London;Fordham University;Oakland Cognitive Behavior Therapy Center and University of California, Berkeley;San Francisco Group for Evidence-Based Psychotherapy and University of California, San Francisco;Institute for Behavioral and Cognitive Psychology and Psychotherapy of Florence (IPSICO);University of Pisa;Institute for Behavioral and Cognitive Psychology and Psychotherapy of Florence (IPSICO);University of Genova;Vanderbilt University;University of Coimbra;Landspítali-University Hospital;Emory University;University of Southern California;Old Dominion University;Virginia Consortium Program in Clinical Psychology;Duke University;Duke Global Health Institute;Duke Global Health Institute;University of California, San Diego;Moi University Medical School;Duke University;Duke Global Health Institute |
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| Abstract: | This study investigated whether a negative interpretation bias was present in people at high risk for psychosis. People with an At Risk Mental State (ARMS; n = 21), patients with First Episode Psychosis (FEP; n = 20), and healthy controls (n = 20) performed three tasks, each of which was designed to measure interpretation bias. Both ARMS and FEP participants showed an attenuated positive bias compared to controls. These findings extend previous results investigating interpretation bias in psychosis by showing that interpretative biases are present before the onset of psychosis, and could therefore contribute to its development. Biased interpretation mechanisms could be a new target for clinical intervention in the early phase of psychosis. |
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