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Extreme Nonresponse to Acute Phase Cognitive Therapy for Depression: An Attempt to Replicate and Extend
Authors:Aaron M. Koenig
Affiliation:Perelman School of Medicine at the University of Pennsylvania, University of Pittsburgh Medical Center; The University of Texas Southwestern Medical Center at Dallas; Perelman School of Medicine at the University of Pennsylvania, West Chester University; Perelman School of Medicine at the University of Pennsylvania; Perelman School of Medicine at the University of Pennsylvania, University of Pittsburgh Medical Center
Abstract:As with other interventions for major depressive disorder (MDD), cognitive therapy (CT) results in treatment failure for about half of all participants. In 2007, Coffman and colleagues in Seattle studied this topic by identifying a group of patients who demonstrated an extremely poor response to CT (i.e., posttreatment BDI score ≥ 31). They called these patients “extreme nonresponders” (ENR) and described the pretreatment characteristics that predicted response status.
Keywords:cognitive therapy (CT)   major depressive disorder (MDD)   nonresponse   predictors of response
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