Diathesis-stress models of psychopathology: A quantitative genetic perspective |
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Authors: | Richard Rende and Robert Plomin |
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Affiliation: | Center for Developmental and Health Genetics, College of Health and Human Development, Pennsylvania State University, University Park, USA |
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Abstract: | When genetics is considered in diathesis-stress models of psychopathology, it is often assumed that heredity provides the diathesis and environmental factors are responsible for the stressor. We discuss two quantitative genetic models relevant to the diathesis-stress construct. One model focuses on genotype-environment interaction, which is the usual way in which genetic influence is represented in diathesis-stress models. A second model—genotype-environment correlation—provides an alternative that represents both genetic and environmental influences relevant to the development of psychopathology. Implications of these models for clinical research are discussed. |
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Keywords: | Diathesis Genotype-environment correlation Genotype-environment interaction Quantitative genetics Stress |
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