Drugs, Environment, Brain, and Behavior |
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| Authors: | Hans S. Crombag Terry E. Robinson |
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| Affiliation: | University of Michigan, Ann Arbor |
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| Abstract: | Abstract— The effects of psychoactive drugs are not just a function of their pharmacological actions, but are due to complex interactions among pharmacological, psychological, and environmental factors. We discuss here how drug-environment interactions determine the likelihood that addictive drugs produce a persistent form of neurobehavioral plasticity (sensitization) thought to be involved in the pathophysiology of addiction and relapse. |
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| Keywords: | sensitization neuroplasticity addiction relapse genes |
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