甲状腺功能亢进症合并烟雾病2例报道并文献复习

探讨甲状腺功能亢进症（甲亢）合并烟雾病的发病机制、临床特点、治疗方法及预后.回顾性分析报道2例甲亢合并烟雾病患者的临床表现、诊疗经过及预后,结合文献分析.甲亢合并烟雾病较为罕见,2例患者均为青年女性,主要表现为以脑梗死为主的脑缺血症状,临床症状均发生于甲状腺毒症期,控制甲亢及血管重建术等治疗可以有效改善神经系统缺损症状,预防复发.对拟诊烟雾病患者筛查甲亢,有脑血管病症状的甲亢患者行脑血管影像学检查,以利于早期发现,综合治疗,预防复发.

2 Cases Report of Hyperthyroidism Associated with Moyamoya Disease and Literature Review

This is to explore the pathogenesis, clinical features, treatment strategies and prognosis of hyperthyroidism associated with moyamoya disease. A retrospective study, reported two cases of hyperthyroidism associated with moyamoya disease patients with clinical manifestations, treatment and prognosis,which were analyzed with the literatures. Coexistence of thyrotoxieosis and moyamoya disease is extremely rare, both of two patients were young women, the main performance were dominated by cerebral ischemie symptoms, occurring in the thyrotoxicosis period, the therapy such as control of hyperthyroidism and revaseularization could improve the neurological coloboma symptoms effectively and prevent recurrence. Screening hyperthyroidism in the cases of suspected moyamoya disease or taking cerebrovascular imaging examination in the cases of hyperthyroidism with cerebral ischemic symptoms were beneficial to early detection, comprehensive treatment and prevent recurrence.