右美托咪定对甲亢患者术中血流动力学的比较研究

研究右美托咪定辅助甲亢患者麻醉诱导时血流动力学的改变。40例甲亢患者，随机分为两组：右美托咪定组（ n＝20）与对照组（n＝20）。记录术前与麻醉诱导后的血压、心率、心率收缩压乘积，抽取静脉血进行儿茶酚胺检测。结果右美托咪定组诱导后、插管后即刻、1分钟、2分钟、3分钟，血压、心率、心率收缩压乘积低于对照组，差异有统计学意义（P＜0．05）。右美托咪定组儿茶酚胺在插管后1分钟、插管后2分钟、插管后3分钟低于对照组差异有统计学意义（P＜0．05）。右美托咪定有利于维持甲亢患者麻醉诱导中血流动力学的稳定。

A Comparative Study about Dexmedetomidine Affecting the Hemodynamics of Hyperthyroidism Patients in surgery

To investigate the changes of hemodynamics in hyperthyoidism patients under anesthesia induction assisted by Dexmedetomidine ,40 hyperthyoidism patients were separated into control group （n= 20） and Dexmedetomidine group （n= 20 ） .Blood pressure , heart rat , heart rate-systolic and blood pressure product were recorded before and after anesthesia induction .And then the concentration of catecholamine was measured in vein .The blood pressure ,heart rat , heart rate-systolic and blood pressure product of Dexmedetomidine group were lower at tracheal intubation ,1 min after tracheal intubation ,2 min after tracheal intubation ,3 min after tracheal intubation than control group （P〈0 .05） .The concentration of catecholamine in Dexmedetomidine group was lower at 1 min after tracheal intubation ,2 min after tracheal intubation ,3 min after tracheal intubation than control group （ P〈 0 .05 ） . Anesthesia induction assisted by Dexmedetomidine was appropriative in hyperthyoidism patients ,and could keep hemodynamics steady .