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Right-hemispheric cortical contributions to language ability in healthy adults |
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| Authors: | Van Ettinger-Veenstra Helene Ragnehed Mattias McAllister Anita Lundberg Peter Engström Maria |
| Affiliation: | a Center for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden b Department of Medical and Health Science, Division of Radiology, Linköping University, Linköping, Sweden c Department of Clinical and Experimental Medicine, Division of Logopedics, Linköping University, Linköping, Sweden d Department of Medical and Health Science, Division of Radiation Physics, Linköping University, Linköping, Sweden e Department of Radiation Physics, CKOC, University Hospital of Linköping, Sweden f Department of Radiology, CKOC, University Hospital of Linköping, Sweden |
| Abstract: | In this study we investigated the correlation between individual linguistic ability based on performance levels and their engagement of typical and atypical language areas in the brain. Eighteen healthy subjects between 21 and 64 years participated in language ability tests, and subsequent functional MRI scans measuring brain activity in response to a sentence completion and a word fluency task. Performance in both reading and high-level language tests correlated positively with increased right-hemispheric activation in the inferior frontal gyrus (specifically Brodmann area 47), the dorsolateral prefrontal cortex (DLPFC), and the medial temporal gyrus (Brodmann area 21). In contrast, we found a negative correlation between performance and left-hemispheric DLPFC activation.Our findings indicate that the right lateral frontal and right temporal regions positively modulate aspects of language ability. |
| Keywords: | Linguistics Functional Magnetic Resonance Imaging Functional laterality Task performance Reading Fluency |
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