Common Genetic and Environmental Influences on Major Depressive Disorder and Conduct Disorder |
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Authors: | Anjali Subbarao Soo Hyun Rhee Susan E Young Marissa A Ehringer Robin P Corley John K Hewitt |
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Institution: | Department of Psychology, University of Colorado, Boulder, CO, USA. |
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Abstract: | The evidence for common genetic and environmental influences on conduct disorder (CD) and major depressive disorder (MDD) in adolescents was examined. A sample of 570 monozygotic twin pairs, 592 dizygotic twin pairs, and 426 non-twin siblings, aged 12-18 years, was recruited from the Colorado Twin Registry. For the past year data, there was a significant correlation between the genetic influences on MDD and CD and, for the lifetime data, there was a significant correlation between the genetic influences on MDD and CD, and a significant correlation between the nonshared environmental influences on MDD and CD. Our results suggest that some genetic factors will increase an individual's vulnerability to both MDD and CD in adolescence. |
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Keywords: | Major depressive disorder Conduct disorder Comorbidity |
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