A portable pupilometer system for measuring pupillary size and light reflex

A new pupilometry assessment system was evaluated as an instrument for potential use in basic research and clinical studies of addictive drug use in humans. The system is portable and can be used as a peripheral device with a variety of IBM-compatible personal computers. The pupilometer electronically measures the pupil diameter with infrared sensors and has the ability to stimulate the pupil with a programmable pulse of light and to record the resultant papillary response. The present report compares the static pupil-diameter measurements obtained with this infrared pupilometer and those obtained photographically in a bench-top and in a clinical setting. The infrared pupilometer was also used to record the light reflex of the pupil in research subjects after administration of various morphine-related drugs. The results indicate that static pupil-diameter measurements made with the infrared pupilometer compare favorably with the photographic measurement. The ability of the infrared pupilometer to record the light reflex may provide an additional means of quantitatively measuring drug action.