| 慢性乙型肝炎的联合抗病毒治疗 |
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| 引用本文： | 陈新月,吴亚松. 慢性乙型肝炎的联合抗病毒治疗[J]. 医学与哲学(人文社会医学版), 2008, 29(7): 13-16 |
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| 作者姓名： | 陈新月 吴亚松 |
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| 作者单位： | 首都医科大学附属佑安医院,北京100069 |
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| 摘 要： | 抗病毒治疗是控制乙型肝炎病原进而防止肝硬化、肝癌等并发症的重要手段。就目前的抗病毒药物而言，单一药物的疗效不能令人满意，越来越多的研究数据表明联合抗病毒治疗，包括干扰素α和核苷（酸）类似物联合治疗以及两种核苷（酸）类似物联合治疗可以减少耐药发生，提高抗病毒疗效。联合抗病毒治疗可能是控制乙肝的有效策略，值得进一步研究。
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| 关 键 词： | 乙肝 联合治疗 干扰素 核苷(酸)类似物 |
Combination Therapy for Chronic Hepatitis B |
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| CHEN Xin-yue,WU Ya-song. Combination Therapy for Chronic Hepatitis B[J]. Medicine & Philosophy:Humanistic & Social Medicine Edition, 2008, 29(7): 13-16 |
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| Authors: | CHEN Xin-yue WU Ya-song |
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| Affiliation: | (Capital Medical University Beijing You-an Hospital ,Beijing 100069 ,China) |
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| Abstract: | Antiviral therapy play a very important role in controlling HBV infection and preventing the development of complications such as cirrhosis,hepatic carcinoma. But so far available antiviral medicines are con-cerned,monotherapy is not so satisfactory. There are increasing evidences show that combination therapy sucn as interferon alpha （pegylated interferon alpha） plus nucleoside/nucleotide analogue or combined two kinds of nucleoside/nucleotide analogues could decrease risk of drug resistance and improve antiviral effect. Combination therapy might be a good choice for chronic hepatitis B and deserve further study. |
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| Keywords: | hepatitis B combination therapy interferon nucleoside/nucleotide analogue |
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