Alcoholism and morphologic findings of the nervous system in autopsy cases

154 autopsy cases of alcoholics (120 men and 34 women) were investigated from a neuropathological viewpoint. In only 19 cases could typical diseases of the nervous system caused by alcoholism be found (Wernicke's encephalopathy, central pontine myelinolysis, Marchiafava-Bignami's disease and disorders of the peripheral nerves and muscles). In comparison liver diseases occurred almost five times more frequently in our own material. Diseases caused by alcoholism of the nervous system, the question of brain shrinkage and its partial reversibility, the up to now not completely known effects on the neurophil and cortical cytoarchitectonic are discussed according to the literature.