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WITHDRAWAL OF CHRONIC CHLORPROMAZINE MEDICATION: AN EXPERIMENTAL ANALYSIS
Authors:David Marholin  Paul E. Touchette  R. Malcolm Stewart
Abstract:Approximately 50% of all institutionalized, mentally retarded adults receive psychotropic medication to control inappropriate behavior. In this study, behaviors exhibited by five retarded adults were formally observed while they were on and off medication. Each subject had been receiving chlorpromazine for six or more years prior to the start of the study. The drug was withdrawn and readministered using a double-blind B-A-B (drug-placebo-drug) design. Effects were highly individualized. Some desirable behavior emerged when chlorpromazine was discontinued.
Keywords:drug-behavior interaction  retardates  chlorpromazine withdrawal  social behavior  workshop behavior  adult retardates
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