The topological inventions of life: From the specialization of multicellular colonies to the functioning of the vertebrate brain

The evolution of biological (intermediary) complexity strongly depends upon the information‐processing advantages it confers to cells and organisms. As a matter of fact, highly complex biological structures such as the cellular signaling system and the vertebrate nervous system have been evolved in order to inform the living system about its surround, subsequently orienting the internal, productive activities. The evolutionary success of these types of informational structures ("infostructures") exemplifies that, almost universally, the “bit” may act as a successful substitute for the “joule”. Recent molecular biology research on cellular signaling systems has disclosed their amazing information‐processing sophistication and the crucial role they play in the formation and functioning of the vertebrate brain. In the neurosciences, duality theory has highlighted the way in which the cortical maps and the cerebral substructures of the vertebrate brain are “topologically” integrated in order to perform an adaptive information‐processing. The development of comprehensive conceptualizations relating brain processing and intracellular processing may well be a strategic step in the development of a vertical “information science”.